报告题目：3-Coordinate Organoboron Compounds Light the Way: Synthesis, Optical Properties and Cell Imaging

报告人：Todd B. Marder院士

报告时间：2019年11月16日（星期六）上午10

报告地点：长安校区启翔楼233会议室

邀请人：纪雷教授

承办学院：柔性电子研究院

联系人：张倩文

联系电话：88460889

报告摘要：

Three-coordinate boron, with a vacant pz-orbital and isoelectronic with a carbonium ion, can conjugate with organic π-systems as a strongp-acceptor in the excited state. Most 3-coordinate boron compounds are Lewis acidic, bind Lewis bases which disrupt this conjugation, and are sensitive to hydrolysis. Bulky substituents on B, such as mesityl (mes) groups, provide steric protection of the vacant p-orbital without disrupting the electronic communication with a π-system, resulting in compounds which are usually air and water stable. In aqueous solution, as required for biological applications, we require additional steric protection to avoid hydrolysis. We focus on the synthesis of dipolar, quadrupolar and octupolar compounds containing B(Ar)₂groups, including those containing newp-acceptors considerably stronger than B(mes)₂, and their linear and nonlinear (2nd and 3rd order NLO, TPA and TPEF) optical properties, and their applications, including one- and two-photo excited fluorescence imaging in live cells.

- J. He, T.B. Marder, et al. “N-Heterocyclic Olefins as Electron Donors in Combination with Triarylborane Acceptors: Synthesis, Optical and Electronic Properties of D-p-A Compounds,”Chem. Eur. J.,2019. DOI: 10.1002/chem.201903118.

- J. Merz, C. Lambert, T.B. Marder, et al. “Synthesis, Photophysical and Electronic Properties of Tetra- Donor- or Acceptor-Substituted ortho-Perylenes Displaying Four Reversible Oxidations or Reductions,”Chem. Sci.,201910, 7516.

- S. Griesbeck, C. Lambert, S. Yamaguchi, T.B. Marder, et al. "The Effect of Branching on One- and Two-Photon Absorption, Cell Viability and Localization of Cationic Triarylborane Chromophores with Dipolar vs. Octupolar Charge Distributions for Cellular Imaging,"Chem. Eur. J.,2019,25, 13164.

- X. Jia, C. Lambert, T.B. Marder, et al. “Triarylborane-Based Helical Donor-Acceptor Compounds: Synthesis, Photophysical and Electronic Properties,”Chem. Eur. J.,2019,25, 10845.

- S. Griesbeck, C. Lambert, S. Yamaguchi, T.B. Marder, et al. “Tuning thep-Bridge of Quadrupolar Triarylborane Chromophores for One- and Two-Photon Ecited Fluorescence Imaging of Lysosomes in Live Cells,”Chem. Sci.,2019,10, 5405.

- T.E. Stennett, T.B. Marder, H. Braunschweig, et al. “Near-Infrared Quadrupolar Chromophores Combining Three-Coordinate Boron-Based Superdonor and Superacceptor Units,”Angew. Chem. Int. Ed.,2019,58, 6449.

- S. Griesbeck, S. Yamaguchi, T.B. Marder, et al. “Optimization of Aqueous Stability versusp-Conjugation in Tetracationic Bis(triarylborane) Chromophores: Applications in Live-Cell Imaging,”Chem. Eur. J.,2019,25, 7679.

- L. Ji, T.B. Marder, et al. “Synthesis, Photophysical, and Electrochemical Properties of Pyrenes Substituted with Donors or Acceptors at the 4- or 4,9-Positions,”J. Org. Chem.,2018,83, 3599.

- J. Merz, C. Lambert, L. Ji, T.B. Marder, et al. “Pyrene MO Shuffle – Controlling Excited State and Redox Properties by Changing the Nature of the Frontier Orbitals,”Chem. Eur. J.,2017,23, 13164.

-S. Griesbeck, T. B. Marder, et al. “Water-Soluble Triarylborane Chromophores for One- and Two-Photon Excited Fluorescence Imaging of Mitochondria in Cells,”Chem. Eur. J.,2016,22, 14701.

- L. Ji, T.B. Marder, et al.“Electron Delocalization in Reduced Forms of 2-(BMes₂)pyrene and 2,7-Bis(BMes₂)pyrene,”J. Am. Chem. Soc.,2015,137, 6750.

- Z. Zhang, T. B. Marder, et al.“Taming the Beast: Fluoromesityl Groups Induce a Dramatic Stability Enhancement in Boroles,”Chem. Sci.,2015,6, 5922.

- Z. Zhang, T. B. Marder, et al.“D-π-A Triarylboron Compounds with Tunable Push-Pull Character Achieved by Modification of Both the Donor and Acceptor Moieties,”Chem. Eur. J.,2015, 21, 177.

- Z. Zhang, T.B. Marder, et al.“Optical and Electronic Properties of Air-stable Organoboron Compounds with Strongly Electron-accepting Bis(fluoromesityl)boryl Groups,”Chem. Sci.,2015, 6, 308.

- Reviews: L. Ji, S. Griesbeck, and T. B. Marder, “Recent Developments in and Perspectives on Three-Coordinate Boron Materials: A Bright Future,” Chem. Sci.,2017,8, 846; C.D. Entwistle and T.B. Marder, “Applications of Three-Coordinate Organoboron Compounds and Polymers in Optoelectronics,”Chem. Mater.,2004, 16, 4574; C.D. Entwistle and T.B. Marder, "Boron Chemistry Lights the Way: Optical Properties of Molecular and Polymeric Systems,"Angew. Chem. Int. Ed. Engl.,2002, 41, 2927.

报告人简介：

Todd B. Marder，德国维尔茨堡大学化学系教授，欧洲科学院院士、巴伐利亚科学院院士、英国皇家化学会会士。Marder教授于1976年在麻省理工学院获得学士学位、1981年在美国加利福尼亚大学获得博士学位之后，先后任英国布里斯托大学从事博士后、杜邦化学高级研究员、加拿大滑铁卢大学助理教授（1985）、副教授（1989），于1992年升任教授，1997年起任英国杜伦大学讲席教授，2012年起任德国Universität Würzburg无机化学研究所讲席教授。

Marder教授是国际知名金属有机化学专家，其研究工作主要集中在金属-硼及有机-硼化学(如过渡金属催化的硼化反应、C-H键的选择性功能化、有机硼光电功能材料等)，至今已在J. Am. Chem. Soc., Angew. Chem. Int. Ed.等国际顶级学术期刊上发表论文340多篇，被引超过22000次，H-index为83。Marder教授曾先后荣获Royal Society of Chemistry Award in Main Group Element Chemistry (2008)及Royal Society Wolfson Research Merit Award (2010)等多项学术奖励。Marder教授长期担任Organometallics, Inorganic Chemistry、the Journal of Organometallic Chemistry、Polyhedron、Inorganica Chimica Acta、Applied Organometallic Chemistry、the Canadian Journal of Chemistry、the Chinese Journal of Chemistry、Crystal Engineering等国际学术期刊编委，应邀在国际学术会议或国际主流大学作学术报告300多场次，是英国杜伦大学、纽卡斯尔大学荣誉教授、香港科技大学、山东大学等多所高校的客座教授。